# 8five8 Therapeutics: Developing a new class of targeted therapy to improve the lives of cancer patients

> ETX\-19477 is a selective PARG inhibitor designed to address DNA damage response vulnerabilities and expand precision treatment options for patients with advanced solid tumors\.

Generated by Yoast SEO v27.8, this is an llms.txt file, meant for consumption by LLMs.

## Pages
- [Team](https://8five8tx.com/team/)
- [Science](https://8five8tx.com/science/)
- [News](https://8five8tx.com/news/)
- [Contact](https://8five8tx.com/contact/)
- [Board of Directors](https://8five8tx.com/board/)

## Posts
- [858 Therapeutics Announces FDA Fast Track Designation for PARG Inhibitor ETX\-19477 for the Treatment of Patients with BRCA\-Mutated, Platinum\-Resistant Ovarian Cancer Share](https://8five8tx.com/858-therapeutics-announces-fda-fast-track-designation-for-parg-inhibitor-etx-19477-for-the-treatment-of-patients-with-brca-mutated-platinum-resistant-ovarian-cancer-share/)
- [858 Therapeutics Announces Initial Data from First\-in\-Human Phase 1/2 Trial of PARG Inhibitor ETX\-19477 to be Presented at 2026 ASCO Annual Meeting](https://8five8tx.com/858-therapeutics-announces-initial-data-from-first-in-human-phase-1-2-trial-of-parg-inhibitor-etx-19477-to-be-presented-at-2026-asco-annual-meeting/)

## Team
- [Jeffrey Stafford, Ph\.D\.](https://8five8tx.com/team/jeffrey-stafford-ph-d/)
- [Jeffrey Stafford, Ph\.D\.](https://8five8tx.com/team/jeffrey-stafford-ph-d-2/)
- [Gretchen Bain, Ph\.D\.](https://8five8tx.com/team/gretchen-bain-ph-d/)
- [Sanjay Trehan, MBA](https://8five8tx.com/team/sanjay-trehan-mba/)
- [Umi Chong](https://8five8tx.com/team/umi-chong/)

## Headers
- [Header 1](https://8five8tx.com/?post_type=us_header&p=13)

## Page Templates
- [Leadership Page Template](https://8five8tx.com/?post_type=us_content_template&p=261)
- [Board Page Template](https://8five8tx.com/?post_type=us_content_template&p=333)
- [News Template 2](https://8five8tx.com/?post_type=us_content_template&p=543)
- [News Template](https://8five8tx.com/?post_type=us_content_template&p=375)

## Reusable Blocks
- [Contact Block](https://8five8tx.com/?post_type=us_page_block&p=460)
- [News Footer](https://8five8tx.com/?post_type=us_page_block&p=384)
- [Team Footer](https://8five8tx.com/?post_type=us_page_block&p=306)
- [Global Footer](https://8five8tx.com/?post_type=us_page_block&p=57)

## Grid Layouts
- [Team](https://8five8tx.com/?post_type=us_grid_layout&p=236)
- [News](https://8five8tx.com/?post_type=us_grid_layout&p=412)

## Categories
- [Uncategorized](https://8five8tx.com/category/uncategorized/)

## Team Categories
- [Leadership](https://8five8tx.com/team_category/leadership/)
- [Board](https://8five8tx.com/team_category/board/)

## Optional
- [Sitemap index](https://8five8tx.com/sitemap_index.xml)